Evaluation methods for Traditional Chinese Medicine large language models: A clinical practice study

Objective: To address the critical gap that existing medical large language model evaluation systems are predominantly based on Western medical paradigms and lack specialized assessment standards for the field of traditional Chinese medicine (TCM), this study constructs a comprehensive evaluation framework specifically designed for TCM clinical large language models, providing scientific assessment tools for their development, validation, and clinical application. Methods: This framework addresses the critical issue of missing TCM evaluation standards by incorporating TCM-specific elements such as pattern differentiation and treatment determination, as well as formula and herb recommendations, while emphasizing patient safety and data privacy. Results: The framework encompasses three core dimensions: (1) clinical scenario coverage and authenticity, including renowned physician case mining, pattern identification assistance, and therapy recommendations; (2) core diagnostic and therapeutic capability support, including symptom terminology recognition, pattern identification reasoning, and medical record generation; and (3) clinical application maturity and safety assurance, including data diversity, output reliability, and privacy protection. Conclusion: This evaluation system provides essential tools for the development and clinical deployment of TCM large language models, facilitating the responsible integration of AI technology into traditional medicine practice while preserving the theoretical integrity of TCM.

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Publication Details

Journal
Guidelines and Standards of Chinese Medicine
Published
2026-08-13
DOI
https://doi.org/10.1097/gscm.0000000000000123
Primary Topic
Traditional Chinese Medicine Studies
Type
article
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article

Evaluation methods for Traditional Chinese Medicine large language models: A clinical practice study

Yuping Zhao, Nanxing Xian, Lei Zhang, Wentong Zhu et al.
Guidelines and Standards of Chinese Medicine
Traditional Chinese Medicine Studies
article

Evaluation methods for Traditional Chinese Medicine large language models: A clinical practice study

Yuping Zhao, Nanxing Xian, Lei Zhang, Wentong Zhu, Hengyi TIan, Yiqing Liu
article en

Abstract

Objective: To address the critical gap that existing medical large language model evaluation systems are predominantly based on Western medical paradigms and lack specialized assessment standards for the field of traditional Chinese medicine (TCM), this study constructs a comprehensive evaluation framework specifically designed for TCM clinical large language models, providing scientific assessment tools for their development, validation, and clinical application. Methods: This framework addresses the critical issue of missing TCM evaluation standards by incorporating TCM-specific elements such as pattern differentiation and treatment determination, as well as formula and herb recommendations, while emphasizing patient safety and data privacy. Results: The framework encompasses three core dimensions: (1) clinical scenario coverage and authenticity, including renowned physician case mining, pattern identification assistance, and therapy recommendations; (2) core diagnostic and therapeutic capability support, including symptom terminology recognition, pattern identification reasoning, and medical record generation; and (3) clinical application maturity and safety assurance, including data diversity, output reliability, and privacy protection. Conclusion: This evaluation system provides essential tools for the development and clinical deployment of TCM large language models, facilitating the responsible integration of AI technology into traditional medicine practice while preserving the theoretical integrity of TCM.

Guidelines and Standards of Chinese Medicine
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Tianjin Municipal Engineering Design and Research Institute (CN)
Openalex Percentile: Top 5%
Traditional Chinese Medicine Studies
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Evaluation methods for Traditional Chinese Medicine large language models: A clinical practice study — Yuping Zhao, Nanxing Xian, et al. · Guidelines and Standards of Chinese Medicine (2026) | TGRS Research Map | TGRS