Expanding CIRdb, a comprehensive catalog of whole-exome sequencing data of Canary Islanders.
) gene, which is associated with body mass index, cardiovascular health, and metabolic and respiratory traits. Taken together, our findings show that CIRdb presents a valuable resource of exome-wide genetic variation in a population at the edge of Southwestern European genetic diversity.
Authors
- Ana Díaz-de Usera (ORCID: https://orcid.org/0000-0002-5001-3673)
- David Jáspez (ORCID: https://orcid.org/0000-0001-7923-0068)
- C Flores
- Almudena Corrales
- Adrián Muñoz‐Barrera (ORCID: https://orcid.org/0000-0002-1561-5898)
- Rafaela González‐Montelongo (ORCID: https://orcid.org/0000-0001-9022-8663)
- Itahisa Marcelino-Rodríguez
- Luis A. Rubio-Rodríguez
- María del Cristo Rodriguez-Perez
- Raquel Cruz-Guerrero
- Beatriz Guillen-Guio
- Ángel Carracedo
- Antonio Cabrera-de León
- Jose M Lorenzo-Salazar
Institutions
- University of Leicester (GB)
- Universidad de La Laguna (ES)
- Universidade de Santiago de Compostela (ES)
- Hospital Universitario de Canarias (ES)
- Instituto de Salud Carlos III (ES)
- Hospital Universitario Nuestra Señora de Candelaria (ES)
- Universidad Fernando Pessoa Canarias (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Instituto Tecnológico y de Energías Renovables (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Center for Research in Molecular Medicine and Chronic Diseases (ES)
- Fundación Pública Galega de Medicina Xenómica (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Instituto de Investigación de Enfermedades Raras (ES)
- NIHR Leicester Biomedical Research Centre (GB)
Publication Details
- Journal
- PubMed
- Published
- 2026-08-21
- DOI
- https://doi.org/10.1016/j.isci.2026.117146
- Primary Topic
- Genetics and Physical Performance
- Type
- article
- Field-Weighted Citation Impact
- 0.00