Designing clinical AI for patient-centered support beyond the visit: the PACT framework for health systems

Clinical AI has advanced rapidly for bounded in-visit tasks such as prediction, documentation, and message generation, yet many costly failures in care occur outside the encounter when follow-up, handoffs, and communication break down. We argue that the next challenge for clinical AI is not only better task performance, but better operational follow-through across the care journey. We propose the PACT framework (Patient-centered, AI-enabled Continuity and Timely action) that reframes clinical AI as a health system function designed to support continuity, completion, escalation, and equity across pre-visit, visit, and post-visit care. The PACT framework specifies the operational elements required for accountable action, including ownership, communication channels, confirmation rules, escalation pathways, and outcome measures. We illustrate its practical use through post-visit coordination, a high-impact setting in which health systems can test workflow integration, monitoring, and tiered human support.

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Publication Details

Journal
npj Health Systems
Published
2026-08-05
DOI
https://doi.org/10.1038/s44401-026-00116-w
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

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article

Designing clinical AI for patient-centered support beyond the visit: the PACT framework for health systems

Charles Safran, Saif Khairat
npj Health Systems
Artificial Intelligence in Healthcare and Education
article

Designing clinical AI for patient-centered support beyond the visit: the PACT framework for health systems

Charles Safran, Saif Khairat
article en

Abstract

Clinical AI has advanced rapidly for bounded in-visit tasks such as prediction, documentation, and message generation, yet many costly failures in care occur outside the encounter when follow-up, handoffs, and communication break down. We argue that the next challenge for clinical AI is not only better task performance, but better operational follow-through across the care journey. We propose the PACT framework (Patient-centered, AI-enabled Continuity and Timely action) that reframes clinical AI as a health system function designed to support continuity, completion, escalation, and equity across pre-visit, visit, and post-visit care. The PACT framework specifies the operational elements required for accountable action, including ownership, communication channels, confirmation rules, escalation pathways, and outcome measures. We illustrate its practical use through post-visit coordination, a high-impact setting in which health systems can test workflow integration, monitoring, and tiered human support.

npj Health SystemsVol. 3(1)
University of North Carolina at Chapel Hill (US), University of North Carolina Health Care (US), Harvard University (US)
National Institutes of Health, National Institute of Nursing Research, National Center for Advancing Translational Sciences
Openalex Percentile: Top 12%
Artificial Intelligence in Healthcare and Education
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