A new ursane-type triterpene from the whole plants of Ainsliaea glabra Hemsl
A comprehensive phytochemical investigation of the whole plant extract of Ainsliaea glabra Hemsl. led to the isolation of nine compounds, including a new ursane-type triterpene fatty acid ester named 3β-O-heptadecanoyl-urs-12-ene (1), along with eight known compounds (2–9). Their structures were elucidated based on extensive spectroscopic analysis, including 1D and 2D NMR and HR-ESI-MS, and comparison with the literature. Biological activity evaluation results revealed that compound 1 displayed the most potent tyrosinase inhibitory activity with an IC50 value of 16.7 μg/mL.
Authors
- Yunlong Yu (ORCID: https://orcid.org/0000-0002-1032-7248)
- Jian Ma
- XiaoLi Ma
- Guodong Jiang
- Zhijun Song (ORCID: https://orcid.org/0009-0000-4972-2344)
Institutions
- Ningxia University (CN)
- State Ethnic Affairs Commission (CN)
- Ningxia Medical University (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2026-08-03
- DOI
- https://doi.org/10.1080/14786419.2026.2711124
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00