Plasma Metabolites for Identifying Bacterial Infection in Acute-on-chronic Liver Failure: A Prospective Multicenter Study
Bacterial infection is a key cause of mortality in patients with acute-on-chronic liver failure (ACLF). In this study, we aimed to identify metabolite biomarkers and develop a novel machine learning model for early identification of bacterial infection in ACLF.
Authors
- Shang Jia (ORCID: https://orcid.org/0000-0001-6285-8959)
- Sumeng Li
- Xin Zheng (ORCID: https://orcid.org/0000-0001-9176-8856)
- 孟忠吉
- Beiling Li (ORCID: https://orcid.org/0000-0002-0633-5632)
- Jing Liu (ORCID: https://orcid.org/0000-0001-5588-3865)
- Lining Guo (ORCID: https://orcid.org/0009-0007-3730-3792)
- Xianbo Wang
- Yubao Zheng
- Xiaotian Yang
- Yanhang Gao
- Xiaobo Lu
- Hai Li
- Zhiping Qian
- Guohong Deng
- Yu Shi
- Yan Huang
- Feng Liu
- Hang Jia
Institutions
- Hubei University of Medicine (CN)
- Central South University (CN)
- Army Medical University (CN)
- Xinjiang Medical University (CN)
- Sun Yat-sen University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Second Hospital of Shandong University (CN)
- Shanghai Public Health Clinical Center (CN)
- Wuhan Union Hospital (CN)
- Southwest Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Beijing Ditan Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Huazhong University of Science and Technology (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-08-03
- DOI
- https://doi.org/10.14218/jcth.2026.00384
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- National Science and Technology Major Project