Bilateral Scleritis and Choroidal Infarction in a Postpartum Patient with Antiphospholipid Syndrome

Abstract Purpose: To report a postpartum case of antiphospholipid syndrome (APS) presenting with bilateral scleritis and choroidal infarction. Methods: The patient underwent a comprehensive ophthalmic examination and multimodal imaging. Results: A 32-year-old female presented 3 days postpartum with bilateral anterior scleritis, left-sided posterior scleritis, and bilateral choroidal infarcts. Systemic workup revealed elevated cardiolipin and beta-2 glycoprotein I antibodies, leading to a diagnosis of primary APS. Treatment with corticosteroids and anticoagulation resulted in significant visual improvement and anatomical reconstruction of the ellipsoid zone. Conclusions: Patients with postpartum APS can present with atypical ocular inflammation. Early recognition is essential for prompt systemic evaluation and treatment to support visual recovery.