Development and validation of a predictive risk model for placental abruption in women with pre-eclampsia using SMOTE.

Placental abruption is a serious complication in pregnant women with preeclampsia. This study investigated the risk factors for placental abruption and developed a predictive model using the Synthetic Minority Over-sampling Technique (SMOTE). A total of 280 pregnant women with preeclampsia treated between September 2020 and September 2025 were enrolled and classified into placental abruption and non-placental abruption groups. Logistic regression showed that parity ≥3, severe preeclampsia, anemia, polyhydramnios, and short umbilical cord were independent risk factors for placental abruption. ROC analysis demonstrated that the SMOTE-based model had better predictive performance than the original model, with a higher AUC (0.863, 95% CI: 0.817-0.901 vs 0.792, 95% CI: 0.739-0.838; z=2.163, P=0.031). The SMOTE-based model also showed higher F-score and positive predictive value, although its true positive rate was lower than that of the original model. These findings indicate that a SMOTE-based predictive model may provide useful support for early risk assessment and prevention of placental abruption in women with preeclampsia.

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Publication Details

Journal
PubMed
Published
2026-08-03
DOI
https://doi.org/10.29063/ajrh2026/v30i14.4
Primary Topic
Maternal and fetal healthcare
Type
article
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article

Development and validation of a predictive risk model for placental abruption in women with pre-eclampsia using SMOTE.

Fangfang Wei, Zhijuan Rong, Rong Yang
PubMed
Maternal and fetal healthcare
article

Development and validation of a predictive risk model for placental abruption in women with pre-eclampsia using SMOTE.

Fangfang Wei, Zhijuan Rong, Rong Yang
article en

Abstract

Placental abruption is a serious complication in pregnant women with preeclampsia. This study investigated the risk factors for placental abruption and developed a predictive model using the Synthetic Minority Over-sampling Technique (SMOTE). A total of 280 pregnant women with preeclampsia treated between September 2020 and September 2025 were enrolled and classified into placental abruption and non-placental abruption groups. Logistic regression showed that parity ≥3, severe preeclampsia, anemia, polyhydramnios, and short umbilical cord were independent risk factors for placental abruption. ROC analysis demonstrated that the SMOTE-based model had better predictive performance than the original model, with a higher AUC (0.863, 95% CI: 0.817-0.901 vs 0.792, 95% CI: 0.739-0.838; z=2.163, P=0.031). The SMOTE-based model also showed higher F-score and positive predictive value, although its true positive rate was lower than that of the original model. These findings indicate that a SMOTE-based predictive model may provide useful support for early risk assessment and prevention of placental abruption in women with preeclampsia.

PubMedVol. 30(14)
China Three Gorges University (CN), The Second Affiliated Hospital of Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 5%
Maternal and fetal healthcare
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