Liquid Biopsy in Biliary Tract Cancer: When Tissue is Not Enough
Circulating tumor DNA (ctDNA) profiling detects actionable genomic alterations in advanced biliary tract cancer faster (8 vs 27 days) and more often (90% vs 50%) than tissue, with high concordance. A recent retrospective study establishes clinical validity and a compelling access case for future prospective ctDNA-directed trials.
Authors
- Lewis Au (ORCID: https://orcid.org/0000-0001-5877-8657)
- Jeanne Tie (ORCID: https://orcid.org/0000-0001-9244-2057)
Institutions
- Peter MacCallum Cancer Centre (AU)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2026-08-03
- DOI
- https://doi.org/10.1158/1078-0432.ccr-26-2090
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00