Trial suggests effectiveness of psilocybin for cocaine use disorder

Individuals with cocaine use disorder who received a single dose of psilocybin combined with psychotherapy showed greater reductions in cocaine use relative to active placebo with psychotherapy, a randomized trial has found. No serious adverse events were reported during the trial.

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2026-08-03
DOI
https://doi.org/10.1002/pu.31488
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Trial suggests effectiveness of psilocybin for cocaine use disorder

The Brown University Psychopharmacology Update
Psychedelics and Drug Studies
article

Trial suggests effectiveness of psilocybin for cocaine use disorder

article en

Abstract

Individuals with cocaine use disorder who received a single dose of psilocybin combined with psychotherapy showed greater reductions in cocaine use relative to active placebo with psychotherapy, a randomized trial has found. No serious adverse events were reported during the trial.

The Brown University Psychopharmacology UpdateVol. 37(9)
Good health and well-being
Openalex Percentile: Top 6%
Psychedelics and Drug Studies
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Trial suggests effectiveness of psilocybin for cocaine use disorder · The Brown University Psychopharmacology Update (2026) | TGRS Research Map | TGRS