Intermediaries, indirect local ties, and innovation output: evidence from an interfirm R&D alliance network during the emergence of the biopharmaceutical industry

This study explores the impact of indirect local ties on firms’ innovation output, focusing on the role of intermediaries connecting firms to their indirect partners in an interfirm R&D alliance network. Our findings reveal a positive relationship between indirect local ties and innovation output. Moreover, this study introduces a comparative approach to examine two alliance governance mechanisms, relative governance strength and relative trust. Relative governance strength as a formal governance mechanism, through equity-based vs. non-equity structures, strengthens the positive impact of indirect local ties on firms’ innovation output. Yet, relative trust as an informal, trust-based governance mechanism, through repeated vs. non-repeated partnerships, does not exhibit a significant moderating effect. These insights enhance our understanding of how firms can navigate intermediaries’ self-interested behaviour to optimise innovation output, offering practical implications for strategic alliance management in knowledge-intensive industries.

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Publication Details

Journal
Industry and Innovation
Published
2026-08-03
DOI
https://doi.org/10.1080/13662716.2026.2710708
Primary Topic
Innovation and Knowledge Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Intermediaries, indirect local ties, and innovation output: evidence from an interfirm R&D alliance network during the emergence of the biopharmaceutical industry

John Hagedoorn, Ning Wang
Industry and Innovation
Innovation and Knowledge Management
article

Intermediaries, indirect local ties, and innovation output: evidence from an interfirm R&D alliance network during the emergence of the biopharmaceutical industry

John Hagedoorn, Ning Wang
article en

Abstract

This study explores the impact of indirect local ties on firms’ innovation output, focusing on the role of intermediaries connecting firms to their indirect partners in an interfirm R&D alliance network. Our findings reveal a positive relationship between indirect local ties and innovation output. Moreover, this study introduces a comparative approach to examine two alliance governance mechanisms, relative governance strength and relative trust. Relative governance strength as a formal governance mechanism, through equity-based vs. non-equity structures, strengthens the positive impact of indirect local ties on firms’ innovation output. Yet, relative trust as an informal, trust-based governance mechanism, through repeated vs. non-repeated partnerships, does not exhibit a significant moderating effect. These insights enhance our understanding of how firms can navigate intermediaries’ self-interested behaviour to optimise innovation output, offering practical implications for strategic alliance management in knowledge-intensive industries.

Industry and Innovation
Shanghai Polytechnic University (CN), Universidad de Londres (MX)
National Natural Science Foundation of China
Industry, innovation and infrastructure
Openalex Percentile: Top 7%
Innovation and Knowledge Management
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