The Effect of Low-Intensity Laser Irradiation on GAP-43 Expression in the Hippocampus of Rats

A study was conducted to examine the effects of visible red light phototherapy with a wavelength of 635 nm on the expression of the neuronal protein GAP-43 in the hippocampus of rats. It was shown that the use of PBMT promotes increased GAP-43 synthesis in the hippocampus, with the maximum effect developing by the 6th day of use, which may indicate a cumulative effect of this procedure.

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Publication Details

Journal
Doklady Biochemistry and Biophysics
Published
2026-08-03
DOI
https://doi.org/10.1134/s1607672926600338
Primary Topic
Laser Applications in Dentistry and Medicine
Type
article
Field-Weighted Citation Impact
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article

The Effect of Low-Intensity Laser Irradiation on GAP-43 Expression in the Hippocampus of Rats

E. V. Orlova, V.N. Kotov, I.V. Kastyro, V. V. Malakhovsky et al.
Doklady Biochemistry and Biophysics
Laser Applications in Dentistry and Medicine
article

The Effect of Low-Intensity Laser Irradiation on GAP-43 Expression in the Hippocampus of Rats

E. V. Orlova, V.N. Kotov, I.V. Kastyro, V. V. Malakhovsky, A. A. Tsymbal
article en

Abstract

A study was conducted to examine the effects of visible red light phototherapy with a wavelength of 635 nm on the expression of the neuronal protein GAP-43 in the hippocampus of rats. It was shown that the use of PBMT promotes increased GAP-43 synthesis in the hippocampus, with the maximum effect developing by the 6th day of use, which may indicate a cumulative effect of this procedure.

Doklady Biochemistry and Biophysics
Sechenov University (RU), Russian Cancer Research Center NN Blokhin (RU), Russian Medical Academy of Continuous Professional Education (RU)
Openalex Percentile: Top 10%
Laser Applications in Dentistry and Medicine
DOISourceOpenAlex
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