Diagnostic Challenges of Methanol Poisoning in Resource‐Limited Settings: A Case Series

ABSTRACT Methanol poisoning is a life‐threatening emergency, but diagnosis is challenging in resource‐limited settings lacking toxicology testing. This case series presents three cases of methanol poisoning: two patients with neurological symptoms and unexplained high anion gap metabolic acidosis were initially misdiagnosed as stroke or diabetic ketoacidosis and died after transfer, whereas the third patient received prompt empirical hemodialysis based on clinical suspicion and survived with full recovery. These cases illustrate that early recognition and empirical hemodialysis guided by clinical judgment, without confirmatory toxicology testing, can be life‐saving in resource‐constrained environments.

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Publication Details

Journal
Clinical Case Reports
Published
2026-07-30
DOI
https://doi.org/10.1002/ccr3.73220
Primary Topic
Poisoning and overdose treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic Challenges of Methanol Poisoning in Resource‐Limited Settings: A Case Series

Guanghua Pan, Hongyun Chen, Liangbo Zeng, Baoliang Xiang et al.
Clinical Case Reports
Poisoning and overdose treatments
article

Diagnostic Challenges of Methanol Poisoning in Resource‐Limited Settings: A Case Series

Guanghua Pan, Hongyun Chen, Liangbo Zeng, Baoliang Xiang, Ting Wu, Xianfeng Wu, Deju Li
article en

Abstract

ABSTRACT Methanol poisoning is a life‐threatening emergency, but diagnosis is challenging in resource‐limited settings lacking toxicology testing. This case series presents three cases of methanol poisoning: two patients with neurological symptoms and unexplained high anion gap metabolic acidosis were initially misdiagnosed as stroke or diabetic ketoacidosis and died after transfer, whereas the third patient received prompt empirical hemodialysis based on clinical suspicion and survived with full recovery. These cases illustrate that early recognition and empirical hemodialysis guided by clinical judgment, without confirmatory toxicology testing, can be life‐saving in resource‐constrained environments.

Clinical Case ReportsVol. 14(8)
Anshun University (CN), First Affiliated Hospital of Guangzhou Medical University (CN), Guangzhou Medical University (CN)
Decent work and economic growth
Openalex Percentile: Top 6%
Poisoning and overdose treatments
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