Atypical Autonomic‐Predominant Guillain‐Barré Syndrome With Pandysautonomia Mimicking Parkinsonism and Recurrent Syncope: A Case Report

ABSTRACT Guillain‐Barré syndrome with pandysautonomia can mimic neurodegenerative and cardiogenic conditions, particularly in elderly patients presenting with autonomic symptoms and parkinsonian features. Timely neurologic evaluation and ganglioside antibody testing—especially anti‐GM2—are essential for accurate diagnosis and the initiation of immunotherapy, which may result in significant clinical improvement even in atypical, chronic presentations.

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Publication Details

Journal
Clinical Case Reports
Published
2026-07-30
DOI
https://doi.org/10.1002/ccr3.73222
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Atypical Autonomic‐Predominant Guillain‐Barré Syndrome With Pandysautonomia Mimicking Parkinsonism and Recurrent Syncope: A Case Report

Sangharsha Thapa, Nabel Rajab Basha, Jin Li, Rua Alsaeed
Clinical Case Reports
Peripheral Neuropathies and Disorders
article

Atypical Autonomic‐Predominant Guillain‐Barré Syndrome With Pandysautonomia Mimicking Parkinsonism and Recurrent Syncope: A Case Report

Sangharsha Thapa, Nabel Rajab Basha, Jin Li, Rua Alsaeed
article en

Abstract

ABSTRACT Guillain‐Barré syndrome with pandysautonomia can mimic neurodegenerative and cardiogenic conditions, particularly in elderly patients presenting with autonomic symptoms and parkinsonian features. Timely neurologic evaluation and ganglioside antibody testing—especially anti‐GM2—are essential for accurate diagnosis and the initiation of immunotherapy, which may result in significant clinical improvement even in atypical, chronic presentations.

Clinical Case ReportsVol. 14(8)
Westchester Medical Center (US), Kathmandu University (NP)
Openalex Percentile: Top 9%
Peripheral Neuropathies and Disorders
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