Letter: The Microbiome‐Mediated Impact of Proton Pump Inhibitors on Spontaneous Bacterial Peritonitis
To the Editor, We read with great interest the study by Kitchen and colleagues [1] who showed that exposure to proton pump inhibitors (PPIs) is associated with a distinct microbiological profile in culture-positive spontaneous bacterial peritonitis (SBP).In this study, PPI-exposed patients had a markedly higher prevalence of Gram-positive isolates, particularly Enterococcus spp., Streptococcus spp., and Staphylococcus aureus.
Authors
- Antonio Gasbarrini (ORCID: https://orcid.org/0000-0002-6230-1779)
- Stefano SIMEONI
- Gianluca Ianiro (ORCID: https://orcid.org/0000-0002-8318-0515)
- Francesca Romana Ponziani (ORCID: https://orcid.org/0000-0002-5924-6238)
- Giovanni Gasbarrini
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2026-07-30
- DOI
- https://doi.org/10.1111/apt.70883
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00