BG-YOLO11s: Boundary-Guided YOLO11 with Bézier Contour Augmentation for Brain Tumour Segmentation in T1-CE MRI
Background/Objectives: Accurate delineation of brain tumours on contrast-enhanced MRI remains difficult because lesions can be small, irregular, and weakly separated from adjacent tissue. This study developed BG-YOLO11s, a boundary-guided single-stage instance-segmentation model for T1 contrast-enhanced MRI. Methods: The public Figshare/Cheng dataset, comprising 3064 slices from 233 patients, was converted to YOLO polygon annotations and evaluated using a fixed 70/15/15 image-level split (2144/459/461 slices). Because patient identifiers were not retained in the exported image-and-polygon data, the split was not guaranteed to be patient-disjoint. Bézier Contour Augmentation generated two contour-perturbed training samples per original slice while leaving validation and test data unchanged. BG-YOLO11s extended YOLO11s-seg with dilated context aggregation in the backbone, boundary-enhanced feature fusion in the neck, and a prototype refinement module with differentiable boundary-aware supervision in the segmentation head. Results: In a single run on the held-out image-level test split, BG-YOLO11s achieved 92.4% precision, 88.7% recall, 94.6% mask mAP@50, 68.9% mAP@50–95, and 86.5% IoU. Relative to YOLO11s-seg, the corresponding gains were 3.8 points in mAP@50, 5.8 points in mAP@50–95, and 4.1 points in IoU. A progressive ablation produced incremental gains along the fixed module-addition sequence, but it did not isolate all component interactions or quantify run-to-run uncertainty. Conclusions: BG-YOLO11s improved single-run mask-overlap estimates under the present image-level benchmark. Patient-disjoint retraining, repeated-seed statistics, boundary-specific metrics, complete failure pattern auditing, and external multi-sequence validation are required before broader clinical or deployment claims can be made.
Authors
- Merve Temizer Ersoy (ORCID: https://orcid.org/0000-0003-4364-9144)
- Faruk Özger (ORCID: https://orcid.org/0000-0002-4135-2091)
- İshak Paçal (ORCID: https://orcid.org/0000-0001-6670-2169)
- Mustafa Yurdakul (ORCID: https://orcid.org/0000-0003-0562-4931)
- Javanshir Zeynalov
Institutions
- University of Turku (FI)
- Fenerbahçe University (TR)
- Türkisch-Deutsche Universität (TR)
- Istanbul Commerce University (TR)
- Istanbul University (TR)
- Nakhchivan State University (AZ)
Publication Details
- Journal
- Diagnostics
- Published
- 2026-07-30
- DOI
- https://doi.org/10.3390/diagnostics16152407
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00