Screening for small-airway dysfunction in rheumatoid arthritis: impulse oscillometry detects cases missed by spirometry and chest CT scan

<title>Extract</title> Despite therapeutic advances in rheumatoid arthritis (RA), pulmonary complications remain a concern and account for a substantial proportion of RA-related mortality [1]. RA can involve all lung compartments – airways, parenchyma, vasculature, and pleura – but interstitial lung disease (ILD) is among the most recognized and clinically impactful manifestations [2]. Airway involvement, including preclinical emphysema and small-airway dysfunction (SAD) is under-recognized; it often precedes ILD in RA, and therefore warrants greater attention for early assessment and risk-modification strategies [3, 4].

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Publication Details

Journal
ERJ Open Research
Published
2026-07-30
DOI
https://doi.org/10.1183/23120541.01047-2026
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Screening for small-airway dysfunction in rheumatoid arthritis: impulse oscillometry detects cases missed by spirometry and chest CT scan

Nicolás Roche, T. Hua-Huy, Anh Tuan Dinh‐Xuan, Guillaume Chassagnon et al.
ERJ Open Research
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Screening for small-airway dysfunction in rheumatoid arthritis: impulse oscillometry detects cases missed by spirometry and chest CT scan

Nicolás Roche, T. Hua-Huy, Anh Tuan Dinh‐Xuan, Guillaume Chassagnon, Sven Günther, F. Aubourg, Nhât-Nam Lê-Dông, Hà Pham-Ngoc, Yannick Allanore, Viêt-Quang Pham, Stéphane Hilliquin, Jérôme Avouac
article en

Abstract

<title>Extract</title> Despite therapeutic advances in rheumatoid arthritis (RA), pulmonary complications remain a concern and account for a substantial proportion of RA-related mortality [1]. RA can involve all lung compartments – airways, parenchyma, vasculature, and pleura – but interstitial lung disease (ILD) is among the most recognized and clinically impactful manifestations [2]. Airway involvement, including preclinical emphysema and small-airway dysfunction (SAD) is under-recognized; it often precedes ILD in RA, and therefore warrants greater attention for early assessment and risk-modification strategies [3, 4].

ERJ Open Research
University of Namur (BE), Inserm (FR), Université Paris Cité (FR), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Européen Georges-Pompidou (FR), Institut Cochin (FR)
Good health and well-being
Openalex Percentile: Top 10%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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