Paraneoplastic Adult‐Onset Still's Disease Caused by Mediastinal Lymph Node Carcinoma of Unknown Primary Site, Most Likely Lung Adenocarcinoma

A 73-year-old man presented with fever, polyarthritis and erythema on his back (Figure 1A) and extremities (Figure 1B).Laboratory findings showed leukocytosis and elevated CRP (24 mg/dL), white blood cell (11 800/μL; neutrophil (88%)), GOT (78 U/L), GPT (89 U/L), LDH (382 U/L), ferritin (1023 ng/mL) and IL-6 (143 pg/mL).Autoantibodies were all negative.Contrast enhanced CT revealed swollen mediastinal lymph nodes and pericardial effusion.

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Publication Details

Journal
International Journal of Rheumatic Diseases
Published
2026-07-30
DOI
https://doi.org/10.1111/1756-185x.70804
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
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article

Paraneoplastic Adult‐Onset Still's Disease Caused by Mediastinal Lymph Node Carcinoma of Unknown Primary Site, Most Likely Lung Adenocarcinoma

Yoshinori Taniguchi, Daiki Okada
International Journal of Rheumatic Diseases
Autoimmune and Inflammatory Disorders Research
article

Paraneoplastic Adult‐Onset Still's Disease Caused by Mediastinal Lymph Node Carcinoma of Unknown Primary Site, Most Likely Lung Adenocarcinoma

Yoshinori Taniguchi, Daiki Okada
article en

Abstract

A 73-year-old man presented with fever, polyarthritis and erythema on his back (Figure 1A) and extremities (Figure 1B).Laboratory findings showed leukocytosis and elevated CRP (24 mg/dL), white blood cell (11 800/μL; neutrophil (88%)), GOT (78 U/L), GPT (89 U/L), LDH (382 U/L), ferritin (1023 ng/mL) and IL-6 (143 pg/mL).Autoantibodies were all negative.Contrast enhanced CT revealed swollen mediastinal lymph nodes and pericardial effusion.

International Journal of Rheumatic DiseasesVol. 29(8)
Kochi Medical School Hospital (JP)
Good health and well-being
Openalex Percentile: Top 10%
Autoimmune and Inflammatory Disorders Research
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