The mechanism of Duodenum Mucosal Resurfacing

This project investigates how Duodenum Mucosal Resurfacing (DMR) improves metabolism. Our central hypothesis is that DMR reshapes the gut microbiota and alters bile acid profiles, which in turn activate a vagus nerve–mediated brain–gut axis to regulate blood glucose levels. This study will provide mechanistic insights into DMR as a potential therapy for metabolic diseases.

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Publication Details

Journal
California Digital Library
Published
2026-07-30
DOI
https://doi.org/10.48321/d17fbc862e
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

The mechanism of Duodenum Mucosal Resurfacing

Miao Shi
California Digital Library
Gastrointestinal motility and disorders
article

The mechanism of Duodenum Mucosal Resurfacing

Miao Shi
article en

Abstract

This project investigates how Duodenum Mucosal Resurfacing (DMR) improves metabolism. Our central hypothesis is that DMR reshapes the gut microbiota and alters bile acid profiles, which in turn activate a vagus nerve–mediated brain–gut axis to regulate blood glucose levels. This study will provide mechanistic insights into DMR as a potential therapy for metabolic diseases.

California Digital Library
Chinese University of Hong Kong (HK)
Openalex Percentile: Top 8%
Gastrointestinal motility and disorders
DOIOpen Access PDFOpenAlex
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