Large language models as sources of patient information on robotic knee arthroplasty: a comparative evaluation

BACKGROUND: Robotic-assisted total knee arthroplasty (rTKA) is increasingly used because of its surgical precision. However, inconsistent outcomes and high costs often lead patients to seek additional information from artificial intelligence (AI) tools. Large language models (LLMs) such as ChatGPT-4o, Gemini-2.5-Flash, and DeepSeek-V3 are commonly used, but their reliability and readability in orthopaedics remain unclear. OBJECTIVES: To compare the reliability, usefulness, quality, and readability of responses to common patient questions about rTKA generated by leading LLMs. METHODS: Three LLMs answered 20 frequently asked patient questions (n = 20) identified through Google Trends and expert validation. Three orthopaedic specialists (n = 3) evaluated reliability, usefulness, and overall quality using validated scales, while readability was assessed with standard indices. RESULTS: Inter-rater reliability was good to excellent (ICC = 0.728-0.879). Gemini-2.5-Flash achieved significantly higher reliability and usefulness scores than ChatGPT-4o and DeepSeek-V3 (all p < 0.05). ChatGPT-4o and DeepSeek-V3 produced more readable but less accurate content, revealing an inverse relationship between reliability and readability. CONCLUSIONS: Gemini-2.5-Flash provided the most reliable responses, highlighting the need for supervised integration of LLMs in patient education.

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Publication Details

Journal
The Knee
Published
2026-07-30
DOI
https://doi.org/10.1016/j.knee.2026.104579
Primary Topic
Total Knee Arthroplasty Outcomes
Type
article
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article

Large language models as sources of patient information on robotic knee arthroplasty: a comparative evaluation

Başar Burak Çakmur, Ali Can Koluman, Nezih Ziroğlu, Mehmet Utku Çiftçi et al.
The Knee
Total Knee Arthroplasty Outcomes
article

Large language models as sources of patient information on robotic knee arthroplasty: a comparative evaluation

Başar Burak Çakmur, Ali Can Koluman, Nezih Ziroğlu, Mehmet Utku Çiftçi, E. Çiftçi
article en

Abstract

BACKGROUND: Robotic-assisted total knee arthroplasty (rTKA) is increasingly used because of its surgical precision. However, inconsistent outcomes and high costs often lead patients to seek additional information from artificial intelligence (AI) tools. Large language models (LLMs) such as ChatGPT-4o, Gemini-2.5-Flash, and DeepSeek-V3 are commonly used, but their reliability and readability in orthopaedics remain unclear. OBJECTIVES: To compare the reliability, usefulness, quality, and readability of responses to common patient questions about rTKA generated by leading LLMs. METHODS: Three LLMs answered 20 frequently asked patient questions (n = 20) identified through Google Trends and expert validation. Three orthopaedic specialists (n = 3) evaluated reliability, usefulness, and overall quality using validated scales, while readability was assessed with standard indices. RESULTS: Inter-rater reliability was good to excellent (ICC = 0.728-0.879). Gemini-2.5-Flash achieved significantly higher reliability and usefulness scores than ChatGPT-4o and DeepSeek-V3 (all p < 0.05). ChatGPT-4o and DeepSeek-V3 produced more readable but less accurate content, revealing an inverse relationship between reliability and readability. CONCLUSIONS: Gemini-2.5-Flash provided the most reliable responses, highlighting the need for supervised integration of LLMs in patient education.

The KneeVol. 62
State Hospital (GB), Acıbadem University (TR), Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi (TR), Kent Hastanesi (TR), Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi (TR), Okan University (TR)
Quality Education
Openalex Percentile: Top 8%
Total Knee Arthroplasty Outcomes
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