Photocatalyzed Radical Migration and C–H Oxidation Enabling Access to Terminal Trifluoromethylated Ketones
O-labeling, and UV-vis spectroscopy support a radical pathway. The method exhibits broad substrate scope and good functional group tolerance, providing a practical approach to access terminal trifluoromethylated ketones.
Authors
- Xiao Long (ORCID: https://orcid.org/0000-0001-7141-4102)
- Chun‐Yang He (ORCID: https://orcid.org/0000-0002-0599-7335)
- Qiuli Yao (ORCID: https://orcid.org/0000-0003-1059-2161)
- Man Chen (ORCID: https://orcid.org/0009-0001-4052-2175)
- Yang Huang (ORCID: https://orcid.org/0000-0002-7542-8074)
- Yuhong Ma (ORCID: https://orcid.org/0000-0001-6384-7231)
- Huanyi Guo
Institutions
- Zunyi Medical University (CN)
- Innovation Pharmaceuticals (United States) (US)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-07-26
- DOI
- https://doi.org/10.1021/acs.joc.6c01037
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00