Auger Electron Therapy Enhanced by Heat-Triggered Release of I-125-Labeled DNA-Targeted Compounds within the Tumor Microenvironment

I]I-DOX-loaded TSLs and hyperthermia represents a promising strategy for Auger electron therapy targeting the nuclei of cancer cells.

Authors

Takeshi Fuchigami (ORCID: https://orcid.org/0000-0001-8141-1212)
Masayuki Munekane (ORCID: https://orcid.org/0000-0002-3405-4512)
Kenji Mishiro (ORCID: https://orcid.org/0000-0002-5071-7574)
Hiroaki Echigo
Kazuki Matsunaga (ORCID: https://orcid.org/0009-0002-2121-3497)
Kazuma Ogawa (ORCID: https://orcid.org/0000-0002-1691-7302)
Miki Ozaki

Institutions

Kanazawa University (JP)

Publication Details

Journal: Molecular Pharmaceutics
Published: 2026-07-26
DOI: https://doi.org/10.1021/acs.molpharmaceut.6c00443
Primary Topic: DNA and Nucleic Acid Chemistry
Type: article
Field-Weighted Citation Impact: 0.00

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article

Auger Electron Therapy Enhanced by Heat-Triggered Release of I-125-Labeled DNA-Targeted Compounds within the Tumor Microenvironment

Takeshi Fuchigami, Masayuki Munekane, Kenji Mishiro, Hiroaki Echigo et al.

Jul 26, 2026

Molecular Pharmaceutics

DNA and Nucleic Acid Chemistry

article

Auger Electron Therapy Enhanced by Heat-Triggered Release of I-125-Labeled DNA-Targeted Compounds within the Tumor Microenvironment

Takeshi Fuchigami, Masayuki Munekane, Kenji Mishiro, Hiroaki Echigo, Kazuki Matsunaga, Kazuma Ogawa, Miki Ozaki

July 26, 2026article en

Abstract

I]I-DOX-loaded TSLs and hyperthermia represents a promising strategy for Auger electron therapy targeting the nuclei of cancer cells.

Molecular Pharmaceutics

Kanazawa University (JP)

Good health and well-being

Openalex Percentile: Top 14%

DNA and Nucleic Acid Chemistry

DOI Source OpenAlex

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Auger Electron Therapy Enhanced by Heat-Triggered Release of I-125-Labeled DNA-Targeted Compounds within the Tumor Microenvironment — Takeshi Fuchigami, Masayuki Munekane, et al. · Molecular Pharmaceutics (2026) | TGRS Research Map | TGRS