Catalytic Asymmetric Metallocyclopropanation Reactions Using Chloroform as a Carbyne Equivalent
-aryl substituent of the ligand. Application in the parallel synthesis of enantioenriched 1,2-diarylcyclopropanes bearing pharmaceutically relevant heterocycles is demonstrated.
Authors
- Eric A. Voight (ORCID: https://orcid.org/0000-0002-9542-5356)
- Jonathon M. Young
- Alexander J. Rago (ORCID: https://orcid.org/0000-0002-9621-1974)
- Martin Garcia Chavez (ORCID: https://orcid.org/0009-0007-8525-4681)
- Christopher Uyeda (ORCID: https://orcid.org/0000-0001-9396-915X)
- Raymond Martinez
- Divya Garg
- Luke R. Harrison
Institutions
- Purdue University West Lafayette (US)
- AbbVie (United States) (US)
- Applied Technologies (United States) (US)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-07-26
- DOI
- https://doi.org/10.1021/jacs.6c05240
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00