Exploring ageing as a potential new therapeutic target for schizophrenia

Increased age-related biological changes have been causally linked to various pathologies in the brain, including Alzheimer's and Parkinson's diseases. There is also evidence that schizophrenia could be included in this group of brain disorders that may actually be manifestations of a broader multisystemic premature ageing phenotype.

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Publication Details

Journal
The British Journal of Psychiatry
Published
2026-07-27
DOI
https://doi.org/10.1192/bjp.2026.10746
Primary Topic
Phosphodiesterase function and regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring ageing as a potential new therapeutic target for schizophrenia

Salvador Macip, Julia Rius-Bonet, Julia Gras-Font
The British Journal of Psychiatry
Phosphodiesterase function and regulation
article

Exploring ageing as a potential new therapeutic target for schizophrenia

Salvador Macip, Julia Rius-Bonet, Julia Gras-Font
article en

Abstract

Increased age-related biological changes have been causally linked to various pathologies in the brain, including Alzheimer's and Parkinson's diseases. There is also evidence that schizophrenia could be included in this group of brain disorders that may actually be manifestations of a broader multisystemic premature ageing phenotype.

The British Journal of Psychiatry
University of Leicester (GB), Brain (Germany) (DE), Barcelonaβeta Brain Research Center (ES)
Good health and well-being
Openalex Percentile: Top 15%
Phosphodiesterase function and regulation
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