Pre-Registered Analysis Protocol: Restrictive vs Liberal Fluid Resuscitation in ICU-Admitted Acute Pancreatitis: A Target Trial Emulation Using MIMIC-IV

Pre-registered analysis protocol for a target trial emulation comparing restrictive vs liberal fluid strategies in acute pancreatitis using MIMIC-IV v3.1. Protocol finalized before outcome extraction. Version 1.1 (2026-07-27).

Authors

Yaoqi Xu

Institutions

Lanzhou University Second Hospital (CN)
Lanzhou University (CN)

Publication Details

Journal: Zenodo (CERN European Organization for Nuclear Research)
Published: 2026-07-27
DOI: https://doi.org/10.5281/zenodo.21628579
Primary Topic: Pancreatitis Pathology and Treatment
Type: preprint

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preprint

Pre-Registered Analysis Protocol: Restrictive vs Liberal Fluid Resuscitation in ICU-Admitted Acute Pancreatitis: A Target Trial Emulation Using MIMIC-IV

Yaoqi Xu

Jul 27, 2026

Zenodo (CERN European Organization for Nuclear Research)

Pancreatitis Pathology and Treatment

preprint

Pre-Registered Analysis Protocol: Restrictive vs Liberal Fluid Resuscitation in ICU-Admitted Acute Pancreatitis: A Target Trial Emulation Using MIMIC-IV

Yaoqi Xu

July 27, 2026preprint en

Abstract

Zenodo (CERN European Organization for Nuclear Research)

Lanzhou University Second Hospital (CN), Lanzhou University (CN)

Pancreatitis Pathology and Treatment

DOI Open Access PDF OpenAlex

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