Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low-grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved. This manuscript presents harmonized recommendations for the diagnosis, treatment, and long-term management of pediatric SPN established by the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) in collaboration with the European Reference Network for Pediatric Oncology (ERN PaedCan) after careful review of the literature and experts' opinions refined by selected external reviewers.
Authors
- Sarah Braungart (ORCID: https://orcid.org/0000-0002-1908-2435)
- Yves Réguerre (ORCID: https://orcid.org/0000-0001-7192-046X)
- Maja Česen (ORCID: https://orcid.org/0000-0003-2434-8960)
- Ines B. Brecht (ORCID: https://orcid.org/0000-0001-7973-3300)
- Calogero Virgone (ORCID: https://orcid.org/0000-0002-3651-9416)
- Daniel Orbach (ORCID: https://orcid.org/0000-0002-2520-139X)
- Sabine Irtan (ORCID: https://orcid.org/0000-0001-5596-9570)
- Gianni Bisogno (ORCID: https://orcid.org/0000-0003-4462-5523)
- Ewa Bień (ORCID: https://orcid.org/0000-0002-2091-2686)
- Michael Abele (ORCID: https://orcid.org/0000-0002-9780-603X)
- Andrea C. Ferrari (ORCID: https://orcid.org/0000-0002-4724-0517)
- Jörg Fuchs (ORCID: https://orcid.org/0000-0001-6145-2391)
- Malgorzata A. Krawczyk
- Schneider DT
- Louise Galmiche
- Bilgehan Yalcin
- Ricardo Lopez‐Almarez
- Tal Ben‐Ami
- Michaela Kuhlen
Institutions
- University of Padua (IT)
- University of Augsburg (DE)
- Université Paris Sciences et Lettres (FR)
- Kaplan Medical Center (IL)
- Royal Hospital for Children (GB)
- Ljubljana University Medical Centre (SI)
- Centre Hospitalier Universitaire de Nantes (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Centre Hospitalier Universitaire de La Réunion (RE)
- University Children's Hospital Tübingen (DE)
- Klinikum Dortmund (DE)
- Hospital de Cruces (ES)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Hacettepe University (TR)
- Gdańsk Medical University (PL)
- Institut Curie (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-07-27
- DOI
- https://doi.org/10.1002/1545-5017.70546
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00