Review of the CKiD U25 eGFR Calculator

The CKiD U25 eGFR equations estimate glomerular filtration rate (GFR) in individuals aged 1-25 years with mild to moderate chronic kidney disease (CKD). They use age, height, sex, serum creatinine, and cystatin C values to provide creatinine-based, cystatin C-based, and combined estimates of kidney function for children and adolescents. This review gives an overview of the appropriate use cases, strengths, limitations, and supporting evidence for their clinical application.