Iodine-Catalyzed Carbonyl Desaturation: A One-Pot Synthesis of Flavones
-Michael addition. This protocol is a metal-free approach to carbonyl desaturation with nontoxic DMSO as both the solvent and oxidant, which is especially beneficial for the synthesis of pharmaceutical compounds. Mechanistic studies suggest that the transformation proceeds via a radical pathway.
Authors
- Bao‐Yin Zhao
- Yue Wang (ORCID: https://orcid.org/0000-0003-0098-5359)
- Li-Gang Kou
- Bin-Xuan Zou
- Heng-Xin Mao
Institutions
- Ministry of Education of the People's Republic of China (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-07-26
- DOI
- https://doi.org/10.1021/acs.joc.6c01237
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00