Reviving Data Potential─The Reanalysis-Driven Metabolomics Data Repository MB-POST
Metabolomics investigates an extraordinarily broad chemical space and generates experimental data with substantial potential for reuse in chemistry, biology, and related fields. We developed MB-POST (https://repository.massbank.jp), a new metabolomics mass spectrometry data repository based on a concept distinct from that of existing platforms, to fully realize this potential. MB-POST implements a reanalysis-oriented metadata framework that captures the information essential for data reuse while providing a streamlined submission system that enables the rapid deposition of standardized metabolomics metadata together with experimental data. Since its public pilot release in December 2024, MB-POST has attracted strong community adoption, with more than 170 experimental projects deposited within its first year and a half. Thus, MB-POST provides a practical foundation for the large-scale reuse of metabolomics mass spectrometry data and represents a concrete step toward accelerating open and data-driven scientific research.
Authors
- Akiyasu C. Yoshizawa (ORCID: https://orcid.org/0000-0002-0870-5502)
- Taihei Torigoe (ORCID: https://orcid.org/0009-0008-4761-8090)
- Masatomo Takahashi (ORCID: https://orcid.org/0000-0002-2493-2684)
- Ryosuke Hayasaka (ORCID: https://orcid.org/0000-0002-8340-0784)
- Hiroshi Tsugawa (ORCID: https://orcid.org/0000-0002-2015-3958)
- Akiyoshi Hirayama (ORCID: https://orcid.org/0000-0002-0440-6820)
- T Kiuchi
- Fumio Matsuda (ORCID: https://orcid.org/0000-0003-1091-778X)
- Shujiro Okuda (ORCID: https://orcid.org/0000-0002-7704-8104)
- Motohiro Ogawa
- Y Takahashi (ORCID: https://orcid.org/0000-0002-9194-6293)
- Yoshihiro Izumi (ORCID: https://orcid.org/0000-0003-4608-4652)
- Takaki Oka
- Yuki Matsuzawa
Institutions
- Keio University (JP)
- Kyoto University (JP)
- Niigata University Medical and Dental Hospital (JP)
- Niigata University (JP)
- Tokyo University of Agriculture and Technology (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-07-27
- DOI
- https://doi.org/10.1021/acs.analchem.6c00697
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science
- National Bioscience Database Center