Anti-RBD Single-Chain Variable Fragments Library (scFv Library) Generation toward the Development of a Diagnostic Platform for SARS-CoV-2
values below 4 μg/mL. These findings highlight the potential utility of these scFvs as candidate reagents for the development of improved diagnostic platforms and as scaffolds for next-generation monoclonal antibody-based therapeutics.
Authors
- Kalpana Luthra (ORCID: https://orcid.org/0000-0002-7801-2867)
- Ekta Sachdeva
- Mohd Shoeb Alam
- Harsh Bhakhri
- Sumit Rathore
- Romisa Razvi
- Kulsum Fatima
- Saurabh Sharma
- Manish Tripathi
Institutions
- National Institute of Biological Sciences, Beijing (CN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- ACS Infectious Diseases
- Published
- 2026-07-27
- DOI
- https://doi.org/10.1021/acsinfecdis.6c00269
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Indian Council of Medical Research
- All-India Institute of Medical Sciences
- Science and Engineering Research Board