An interesting case of polypoid endometriosis: Challenging in diagnosis

Objectives: Polypoid endometriosis is a rare presentation of endometriosis which may mimic various pelvic malignancies. In this study, we aim to explain a rare case and review the specific features in multiple imaging modalities for differentiating benign from malignant lesions. Case presentation: The patient was a 27-year-old woman presenting with highly vascular multiloculated solid cystic pelvic mass, separate from ovaries and uterus with high T1 signal in cystic components. There were conflicting appearances ranging from sarcoma to endometriosis related malignancy or benign endometriosis related pathology in ultrasound and MRI. After surgical excision, polypoid endometriosis was confirmed in pathology. Conclusion: The radiologists have to be familiar with imaging characteristics of polypoid endometriosis in different imaging evaluations. Imaging features such as dark T2 signal intensity, lack of diffusion restriction, and smooth border help them to make an accurate diagnosis and appropriate management.

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Publication Details

Journal
Journal of Endometriosis and Pelvic Pain Disorders
Published
2026-07-25
DOI
https://doi.org/10.1177/22840265261468454
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

An interesting case of polypoid endometriosis: Challenging in diagnosis

Soheila Sarmadi, Leila Bayani, Elham Shirali, Behnaz Moradi et al.
Journal of Endometriosis and Pelvic Pain Disorders
Endometriosis Research and Treatment
article

An interesting case of polypoid endometriosis: Challenging in diagnosis

Soheila Sarmadi, Leila Bayani, Elham Shirali, Behnaz Moradi, Reihaneh Mortazavi Ardestani
article en

Abstract

Objectives: Polypoid endometriosis is a rare presentation of endometriosis which may mimic various pelvic malignancies. In this study, we aim to explain a rare case and review the specific features in multiple imaging modalities for differentiating benign from malignant lesions. Case presentation: The patient was a 27-year-old woman presenting with highly vascular multiloculated solid cystic pelvic mass, separate from ovaries and uterus with high T1 signal in cystic components. There were conflicting appearances ranging from sarcoma to endometriosis related malignancy or benign endometriosis related pathology in ultrasound and MRI. After surgical excision, polypoid endometriosis was confirmed in pathology. Conclusion: The radiologists have to be familiar with imaging characteristics of polypoid endometriosis in different imaging evaluations. Imaging features such as dark T2 signal intensity, lack of diffusion restriction, and smooth border help them to make an accurate diagnosis and appropriate management.

Journal of Endometriosis and Pelvic Pain Disorders
Iran University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 7%
Endometriosis Research and Treatment
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