Lyme polyradiculoneuritis case report

We present a challenging case that serves as a cautionary tale pertaining to the appropriate incorporation of electrophysiological assessment of the acute neuromuscular patient. This 64 year-old man presented with acute arm pain and weakness, with electrophysiological assessment suggestive of a brachial plexopathy. Subsequent investigation, however, led to a diagnostic shift to one of a radiculoplexus neuropathy, leading to a revised diagnosis of Lyme Polyradiculoneuritis. This new diagnosis had implications for management. Knowledge of the limitations of electrophysiological assessment is important for both the neuromuscular specialist and general neurologist. The case also bears educational import for the modern practice of neurology in the Appalachian region of the United States, as Lyme disease has become endemic to Appalachia as well.

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Publication Details

Journal
Discover Neuroscience
Published
2026-07-25
DOI
https://doi.org/10.1186/s13064-026-00303-3
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Lyme polyradiculoneuritis case report

Thomas Adam Purvis
Discover Neuroscience
Peripheral Neuropathies and Disorders
article

Lyme polyradiculoneuritis case report

Thomas Adam Purvis
article en

Abstract

We present a challenging case that serves as a cautionary tale pertaining to the appropriate incorporation of electrophysiological assessment of the acute neuromuscular patient. This 64 year-old man presented with acute arm pain and weakness, with electrophysiological assessment suggestive of a brachial plexopathy. Subsequent investigation, however, led to a diagnostic shift to one of a radiculoplexus neuropathy, leading to a revised diagnosis of Lyme Polyradiculoneuritis. This new diagnosis had implications for management. Knowledge of the limitations of electrophysiological assessment is important for both the neuromuscular specialist and general neurologist. The case also bears educational import for the modern practice of neurology in the Appalachian region of the United States, as Lyme disease has become endemic to Appalachia as well.

Discover NeuroscienceVol. 21(1)
West Virginia University (US), Blanchette Rockefeller Neurosciences Institute (US)
Openalex Percentile: Top 8%
Peripheral Neuropathies and Disorders
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