Corticosteroids for Haemophagocytic Lymphohistiocytosis Secondary to Typhoid Fever: A Case Report
ABSTRACT Unlike haemophagocytic lymphohistiocytosis (HLH) induced by tuberculosis or rickettsial disease, there is no consensus for the treatment of HLH secondary to typhoid fever ( Salmonella Typhi). After a short illustrative example, we searched among the previously described cases of HLH secondary to typhoid fever to determine: (i) Is the specific treatment of HLH mandatory; and (ii) which option to choose between corticosteroids and intravenous immunoglobulins in association with antibiotherapy?
Authors
- Aurélie Brunet (ORCID: https://orcid.org/0000-0002-5541-2083)
- Claire Pluchart (ORCID: https://orcid.org/0000-0002-5500-969X)
- S. Baumard
- I. Quatresous
- Yohan N’Guyen (ORCID: https://orcid.org/0000-0001-9092-5071)
Institutions
- Institut d’Hématologie et d’Oncologie Pédiatrique (FR)
- L’Institut du Cancer Courlancy Reims (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Hôpital Robert-Debré (FR)
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- eJHaem
- Published
- 2026-07-25
- DOI
- https://doi.org/10.1002/jha2.70365
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00