Molecular analysis of genes <i>MICA</i> , <i>GPC3, PNPLA3,</i> and <i>TM6SF2</i> polymorphisms in patients of hepatocellular carcinoma
, heterozygous (AG) has a highly significant association with hepatocellular carcinoma, with increased risk of hepatocellular carcinoma by 2-fold. In rs58542926, a homozygous mutant (GG) also shows a substantial correlation with HCC, with increased risk of HCC up to 2-fold. In contrast, the heterozygous (AG) genotype of the rs58542926 SNP shows a highly significant relationship with decreased risk of HCC.
Authors
- M Al-hai Ali
- Kashif Bashir (ORCID: https://orcid.org/0000-0001-7598-0398)
- Rafia Batool
- Wenshuang Zou
- Hafiza Fakhira Ameer
- Maria Nasim
Institutions
- Superior University (PK)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Nucleosides Nucleotides & Nucleic Acids
- Published
- 2026-07-24
- DOI
- https://doi.org/10.1080/15257770.2026.2705881
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00