Impact of Perianal Inflammatory Lesions in Crohn's Disease Patients with Anorectal Cancer

Objectives: Perianal inflammatory lesions (PILs), such as anal fistulas and perianal abscesses, are major complications of perianal Crohn's disease (CD). These lesions reflect inflammation status of CD and pose a risk of carcinogenesis. Their presence may be a risk factor for surgical complications and poor prognosis; however, their impact on CD patients with anorectal cancer is not well understood.

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Publication Details

Journal
Journal of the Anus Rectum and Colon
Published
2026-07-24
DOI
https://doi.org/10.23922/jarc.2025-130
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of Perianal Inflammatory Lesions in Crohn's Disease Patients with Anorectal Cancer

Soichiro Ishihara, Koya Hida, Kazutaka Obama, Tatsuki Noguchi et al.
Journal of the Anus Rectum and Colon
Autoimmune and Inflammatory Disorders
article

Impact of Perianal Inflammatory Lesions in Crohn's Disease Patients with Anorectal Cancer

Soichiro Ishihara, Koya Hida, Kazutaka Obama, Tatsuki Noguchi, Kenichi Sugihara, Takuya Takami, Yusuke Fujii, Nobuaki Hoshino, from the Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers by Japanese Society for Cancer of the Colon and Rectum, Yoichi Ajioka
article en

Abstract

Objectives: Perianal inflammatory lesions (PILs), such as anal fistulas and perianal abscesses, are major complications of perianal Crohn's disease (CD). These lesions reflect inflammation status of CD and pose a risk of carcinogenesis. Their presence may be a risk factor for surgical complications and poor prognosis; however, their impact on CD patients with anorectal cancer is not well understood.

Journal of the Anus Rectum and ColonVol. 10(3)
Tokyo Medical and Dental University (JP), Kyoto University (JP), Niigata University (JP), The University of Tokyo (JP)
Keio University, Fukuoka University, Hyogo College of Medicine
Good health and well-being
Openalex Percentile: Top 8%
Autoimmune and Inflammatory Disorders
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