Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring are essential prior to initiating disulfiram therapy.

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Publication Details

Journal
Clinical Case Reports
Published
2026-07-23
DOI
https://doi.org/10.1002/ccr3.73209
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

Jiann Lin Loo, Bikram Chhetri, Sonam Wangchuk
Clinical Case Reports
Alcohol Consumption and Health Effects
article

Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

Jiann Lin Loo, Bikram Chhetri, Sonam Wangchuk
article en

Abstract

ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring are essential prior to initiating disulfiram therapy.

Clinical Case ReportsVol. 14(8)
Betsi Cadwaladr University Health Board (GB), Teaching Hospital Kandy (LK), Khesar Gyalpo University of Medical Sciences of Bhutan (BT), Royal University of Bhutan (BT)
Good health and well-being
Openalex Percentile: Top 9%
Alcohol Consumption and Health Effects
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