Association of Below-the-Knee Lesions With Occult Coronary Artery Disease in Patients With Lower Extremity Artery Disease Undergoing Endovascular Therapy

Background: In patients with lower extremity artery disease (LEAD), coexisting coronary artery disease (CAD) is common, but the angiographic features associated with occult CAD remain poorly characterized. We performed a hypothesis-generating angiographic phenotyping analysis to examine whether lower extremity lesions treated with endovascular therapy (EVT), particularly below-the-knee (BK) lesions, were associated with coexisting occult CAD on preprocedural coronary computed tomography angiography (CCTA) in patients undergoing EVT.