Reduced sensitization over time to parabens 16% mix in North-eastern Italy, 1997-2023
Despite their widespread use, parabens are some of the least allergenic preservatives. This multicenter study investigated prevalence of sensitization to Parabens mix 16% among 44,446 consecutive patients patch tested for suspected allergic contact dermatitis during 1997–2023 in North-eastern Italy. The reducing time-trend prevalence of paraben sensitization likely reflected progressive lower use of this preservative in recent years, as a result of EU legislation reducing parabens content in cosmetics since 2009.
Authors
- Martina Maurelli (ORCID: https://orcid.org/0000-0001-7492-8010)
- Donatella Sansone
- Francesca Larese Filon (ORCID: https://orcid.org/0000-0002-7717-0417)
- Luca Cegolon
Institutions
- University of Verona (IT)
- University of Trieste (IT)
- Public Health Agency (GB)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2026-07-23
- DOI
- https://doi.org/10.1093/bjd/ljag312
- Primary Topic
- Contact Dermatitis and Allergies
- Type
- article
- Field-Weighted Citation Impact
- 0.00