Organophosphine‐Mediated Reductive Homocoupling of Hydrated α‐Acylaldehydes
A PPh 3 ‐mediated reductive homocoupling reaction of hydrated α‐acylaldehydes via Kukhtin–Ramirez intermediates has been developed. Various hydrated α‐arylacylaldehydes and hydrated α‐alkoxyacylaldehydes are well‐tolerated in this transformation to rapidly assemble 1,4‐dicarbonyl compounds.
Authors
- Wei Zeng (ORCID: https://orcid.org/0000-0002-6113-2459)
- Huanfeng Jiang (ORCID: https://orcid.org/0000-0002-4355-0294)
- Jianzhang Li (ORCID: https://orcid.org/0000-0002-4590-2919)
- Ying Xie (ORCID: https://orcid.org/0000-0002-0237-3244)
- Lixing Shen
Institutions
- Key Laboratory of Guangdong Province (CN)
- Sichuan University of Science and Engineering (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2026-07-23
- DOI
- https://doi.org/10.1002/adsc.70664
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00