Electronic Health Record–Based Best Practice Advisory Improves Guideline-Directed Medical Therapy in Heart Failure With Reduced Ejection Fraction: A Quality Improvement Study

In this pre-post Define, Measure, Analyze, Improve, Control quality improvement study, an Epic electronic health record best practice advisory was implemented to prompt guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction. Documented GDMT prescribing rose markedly from 9.1% to 42.2%, supporting electronic health record-based prompts as an effective strategy for GDMT optimization.