Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome
Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti-mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow-up for lung and thyroid disease.
Authors
- Muhammad Husnain Ahmad (ORCID: https://orcid.org/0009-0006-5248-0749)
- Masab Ali (ORCID: https://orcid.org/0009-0007-8599-6861)
- Abdul Rehman Khan (ORCID: https://orcid.org/0009-0002-4885-0410)
- Ali Gohar (ORCID: https://orcid.org/0000-0002-7357-1977)
- Syeda Eman Fatima
- Humayun Nasir
- Fatima Arshad
- Ira Abid
- Zain Fatima (ORCID: https://orcid.org/0009-0000-7501-6283)
- Abdum Muneeb Sandhu (ORCID: https://orcid.org/0009-0000-5689-4128)
Institutions
- King Edward Medical University (PK)
- Punjab Medical College (PK)
- Lahore General Hospital (PK)
- Central-Asian Institute for Applied Geosciences (KG)
- George Eliot Hospital NHS Trust (GB)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2026-07-24
- DOI
- https://doi.org/10.1002/ccr3.73201
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00