Results of Endovascular Treatment of Ruptured Intracranial Aneurysms and Recanalization Rate After a Five-Year Follow-Up Period

Background/Objectives: Endovascular embolization of ruptured intracranial arterial aneurysms has become the first-choice treatment due to its minimal invasiveness, rapid patient recovery, and lower complication rate. The aim of this study was to analyze putative risk factors of unfavorable outcomes of ruptured intracranial aneurysms after coil embolization and the recanalization rate. Methods: This case series included adult patients with ruptured intracranial aneurysms who underwent endovascular embolization during the study period of 2007–2023. In total, 1080 patients with ruptured intracranial aneurysms treated using endovascular coiling participated in this study. Results: During the first year after the initial intervention, repeated embolization was performed for 50 patients (5.5%). Treatment outcome was assessed using the modified Rankin Scale, and neuroradiological follow-up was conducted during a five-year period on 672 patients. During the period from one to five years, re-embolization was performed in 11 (1.5%) cases, of which only three occurred during the last 3 years of follow-up. Conclusions: Endovascular embolization is a safe method for the treatment of ruptured intracranial aneurysms, with a low complication rate and good clinical outcome. Higher risk for repeated aneurysm embolization is associated with male sex, alcohol consumption, smoking, hyperlipidemia, aneurysm size, diabetes, aneurysm location, and obliteration rate. This study showed that aneurysms in which recanalization is not observed within 2 years after coil embolization remain stable during a follow-up period of 5 years, except in the case of large aneurysms and low obliteration rates.

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Journal
Journal of Clinical Medicine
Published
2026-07-23
DOI
https://doi.org/10.3390/jcm15155756
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
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article

Results of Endovascular Treatment of Ruptured Intracranial Aneurysms and Recanalization Rate After a Five-Year Follow-Up Period

Stevan Eric, Nemanja Jovanović, Marina Miletić Kovačević, Vojin Kovačević et al.
Journal of Clinical Medicine
Intracranial Aneurysms: Treatment and Complications
article

Results of Endovascular Treatment of Ruptured Intracranial Aneurysms and Recanalization Rate After a Five-Year Follow-Up Period

Stevan Eric, Nemanja Jovanović, Marina Miletić Kovačević, Vojin Kovačević, Nemanja Petrović, Jelena Nešić, Nikola Mirković, Snežana Lukić, Dragi Bankovi, Marko Petrović, Nenad J. Zornić
article en

Abstract

Background/Objectives: Endovascular embolization of ruptured intracranial arterial aneurysms has become the first-choice treatment due to its minimal invasiveness, rapid patient recovery, and lower complication rate. The aim of this study was to analyze putative risk factors of unfavorable outcomes of ruptured intracranial aneurysms after coil embolization and the recanalization rate. Methods: This case series included adult patients with ruptured intracranial aneurysms who underwent endovascular embolization during the study period of 2007–2023. In total, 1080 patients with ruptured intracranial aneurysms treated using endovascular coiling participated in this study. Results: During the first year after the initial intervention, repeated embolization was performed for 50 patients (5.5%). Treatment outcome was assessed using the modified Rankin Scale, and neuroradiological follow-up was conducted during a five-year period on 672 patients. During the period from one to five years, re-embolization was performed in 11 (1.5%) cases, of which only three occurred during the last 3 years of follow-up. Conclusions: Endovascular embolization is a safe method for the treatment of ruptured intracranial aneurysms, with a low complication rate and good clinical outcome. Higher risk for repeated aneurysm embolization is associated with male sex, alcohol consumption, smoking, hyperlipidemia, aneurysm size, diabetes, aneurysm location, and obliteration rate. This study showed that aneurysms in which recanalization is not observed within 2 years after coil embolization remain stable during a follow-up period of 5 years, except in the case of large aneurysms and low obliteration rates.

Journal of Clinical MedicineVol. 15(15)
University of Kragujevac (RS), Clinical Centre of Kragujevac (RS)
Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja, Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu
Good health and well-being
Openalex Percentile: Top 9%
Intracranial Aneurysms: Treatment and Complications
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