Clinical Factors Related to Cardiac Conduction Disturbance in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy Undergoing Tafamidis Treatment

Background: Cardiac conduction disturbances are frequently observed in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). Because their relationships with other clinical factors have not been fully investigated, in this study we evaluated changes in atrioventricular conduction disturbances (AVCD) and intraventricular conduction disturbances (IVCD) in patients with ATTR-CM undergoing tafamidis treatment, with the aim of identifying clinical factors, including cardiac magnetic resonance (CMR) parameters, related to AVCD and IVCD.

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Publication Details

Journal
Circulation Reports
Published
2026-07-23
DOI
https://doi.org/10.1253/circrep.cr-26-0177
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
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article

Clinical Factors Related to Cardiac Conduction Disturbance in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy Undergoing Tafamidis Treatment

Fuminari Tatsugami, Toshiro Kitagawa, Daiki Okamoto, Yoshiharu Sada et al.
Circulation Reports
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Clinical Factors Related to Cardiac Conduction Disturbance in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy Undergoing Tafamidis Treatment

Fuminari Tatsugami, Toshiro Kitagawa, Daiki Okamoto, Yoshiharu Sada, Kotaro Hamamoto, Yukiko Nakano
article en

Abstract

Background: Cardiac conduction disturbances are frequently observed in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). Because their relationships with other clinical factors have not been fully investigated, in this study we evaluated changes in atrioventricular conduction disturbances (AVCD) and intraventricular conduction disturbances (IVCD) in patients with ATTR-CM undergoing tafamidis treatment, with the aim of identifying clinical factors, including cardiac magnetic resonance (CMR) parameters, related to AVCD and IVCD.

Circulation Reports
Hiroshima University (JP)
Good health and well-being
Openalex Percentile: Top 15%
Amyloidosis: Diagnosis, Treatment, Outcomes
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