Dietary Protein Intake and Low Muscle Strength in Women with Breast Cancer: An Association Study

Women with breast cancer experience body composition and dietary changes, which may lead to reduced muscle strength (MS) and muscle mass. This study aimed to analyze the relationship between MS and dietary protein intake in this population. A cross-sectional study was conducted with women aged over 20 years diagnosed within ≤12 months. Sociodemographic, behavioral, clinical, and anthropometric data were collected. MS was assessed based on handgrip strength. Food intake was estimated using a food frequency questionnaire. Adjusted binary logistic regression was performed (p < 0.05). The sample comprised 149 women (mean age: 55.6 ± 11.2 years). Most participants self-identified as black or brown (67.1%), had invasive lobular carcinoma (66.4%), and were overweight (35.6%), while 28.2% exhibited low grip strength. The group with low MS had higher intakes of carbohydrates, plant protein, and magnesium as well as lower intakes of total fat, total protein, and animal protein (p < 0.05 for all). Each additional gram/day of animal protein was associated with a 7% reduction in the likelihood of having low muscle strength (β = −0.042; OR = 0.93; 95% CI: 0.921–0.977; p = 0.035). Animal protein intake was inversely associated with low muscle strength in women with breast cancer.

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Journal
Nutrition and Cancer
Published
2026-07-23
DOI
https://doi.org/10.1080/01635581.2026.2703314
Primary Topic
Nutrition and Health in Aging
Type
article
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article

Dietary Protein Intake and Low Muscle Strength in Women with Breast Cancer: An Association Study

José Luiz Marques-Rocha, Maria Rita Pereira da Silva Garcia, Ana Beatriz Rechinelli, Valdete Regina Guandalini et al.
Nutrition and Cancer
Nutrition and Health in Aging
article

Dietary Protein Intake and Low Muscle Strength in Women with Breast Cancer: An Association Study

José Luiz Marques-Rocha, Maria Rita Pereira da Silva Garcia, Ana Beatriz Rechinelli, Valdete Regina Guandalini, Luisa Barcellos Leite da Silva, Rayne de Almeida Marques Bernabé, Ben‐Hur Albergaria, Janine Martins Machado, Deborah Minto dos Santos, Julia Abdala Nogueira Souza
article en

Abstract

Women with breast cancer experience body composition and dietary changes, which may lead to reduced muscle strength (MS) and muscle mass. This study aimed to analyze the relationship between MS and dietary protein intake in this population. A cross-sectional study was conducted with women aged over 20 years diagnosed within ≤12 months. Sociodemographic, behavioral, clinical, and anthropometric data were collected. MS was assessed based on handgrip strength. Food intake was estimated using a food frequency questionnaire. Adjusted binary logistic regression was performed (p < 0.05). The sample comprised 149 women (mean age: 55.6 ± 11.2 years). Most participants self-identified as black or brown (67.1%), had invasive lobular carcinoma (66.4%), and were overweight (35.6%), while 28.2% exhibited low grip strength. The group with low MS had higher intakes of carbohydrates, plant protein, and magnesium as well as lower intakes of total fat, total protein, and animal protein (p < 0.05 for all). Each additional gram/day of animal protein was associated with a 7% reduction in the likelihood of having low muscle strength (β = −0.042; OR = 0.93; 95% CI: 0.921–0.977; p = 0.035). Animal protein intake was inversely associated with low muscle strength in women with breast cancer.

Nutrition and Cancer
Instituto Federal do Espírito Santo (BR), Universidade Federal do Espírito Santo (BR)
Zero hunger
Openalex Percentile: Top 9%
Nutrition and Health in Aging
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