Considerations in Genomic Therapy Matching

To the Editor Lin et al1 report an important analysis of genomic therapy matching in rare and refractory cancers. The finding that improved survival was seen with clinically supported matches but not with investigational tiers is particularly interesting and clinically relevant.

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Publication Details

Journal
JAMA Oncology
Published
2026-07-23
DOI
https://doi.org/10.1001/jamaoncol.2026.2248
Primary Topic
Genomic variations and chromosomal abnormalities
Type
article
Field-Weighted Citation Impact
0.00
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article

Considerations in Genomic Therapy Matching

Polina Shilo
JAMA Oncology
Genomic variations and chromosomal abnormalities
article

Considerations in Genomic Therapy Matching

Polina Shilo
article en

Abstract

To the Editor Lin et al1 report an important analysis of genomic therapy matching in rare and refractory cancers. The finding that improved survival was seen with clinically supported matches but not with investigational tiers is particularly interesting and clinically relevant.

JAMA Oncology
Saint Petersburg State Pediatric Medical University (RU)
Openalex Percentile: Top 9%
Genomic variations and chromosomal abnormalities
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Considerations in Genomic Therapy Matching — Polina Shilo · JAMA Oncology (2026) | TGRS Research Map | TGRS