Association of Low-Attenuation Noncalcified Plaque Shape and Degree of Intraplaque Embeddedness Using Atherosclerotic Imaging–enabled Quantitative CT with Acute Coronary Syndrome
Adverse low-attenuation noncalcified plaque morphology using atherosclerotic imaging-enabled quantitative CT (ie, lobular, bean, or spherical low-attenuation noncalcified plaque shape or low-attenuation noncalcified plaque with ≥ 180° of embeddedness) was independently associated with acute coronary syndrome.
Authors
- Daniele Andreini (ORCID: https://orcid.org/0000-0002-5996-9209)
- Jagat Narula (ORCID: https://orcid.org/0000-0002-0280-3996)
- Jonathon A Leipsic (ORCID: https://orcid.org/0000-0002-6133-8334)
- Todd C. Villines (ORCID: https://orcid.org/0000-0003-2674-3702)
- Kavitha M. Chinnaiyan (ORCID: https://orcid.org/0000-0002-1337-826X)
- Hugo Marques (ORCID: https://orcid.org/0000-0001-8210-2075)
- Ji Min Sung (ORCID: https://orcid.org/0000-0003-1958-7596)
- Habib Samady (ORCID: https://orcid.org/0000-0002-5722-7252)
- Filippo Cademartiri (ORCID: https://orcid.org/0000-0002-0579-3279)
- Iksung Cho (ORCID: https://orcid.org/0000-0001-5927-5410)
- Ran Heo (ORCID: https://orcid.org/0000-0002-2675-3612)
- Leslee J. Shaw (ORCID: https://orcid.org/0000-0003-1268-1491)
- Nick S. Nurmohamed (ORCID: https://orcid.org/0000-0001-9045-6009)
- Benjamin J.W. Chow (ORCID: https://orcid.org/0000-0001-8631-0234)
- Martin Hadamitzky (ORCID: https://orcid.org/0000-0001-6267-1692)
- Ibrahim Danad (ORCID: https://orcid.org/0000-0002-3140-1320)
- James P. Earls (ORCID: https://orcid.org/0000-0001-6343-3661)
- Erica Maffei (ORCID: https://orcid.org/0000-0002-0388-4433)
- Ricardo C. Cury (ORCID: https://orcid.org/0000-0001-6948-2886)
- Lohendran Baskaran (ORCID: https://orcid.org/0000-0003-0565-7151)
- Jeroen Joost Bax (ORCID: https://orcid.org/0000-0001-7368-0500)
- Edoardo Conte (ORCID: https://orcid.org/0000-0003-1443-5788)
- Andrew Choi (ORCID: https://orcid.org/0000-0003-0232-1994)
- Udo Hoffman
- Hyung‐Bok Park (ORCID: https://orcid.org/0000-0002-3773-2665)
- Renu Virmani (ORCID: https://orcid.org/0000-0003-1879-0015)
- Gianluca Pontone (ORCID: https://orcid.org/0000-0002-1339-6679)
- Crabtree Ts
- Fay Y. Lin (ORCID: https://orcid.org/0000-0001-8604-8715)
- Peter H. Stone (ORCID: https://orcid.org/0000-0001-6031-3699)
- Hyuk‐Jae Chang (ORCID: https://orcid.org/0000-0002-6139-7545)
- Sabee Molloi (ORCID: https://orcid.org/0000-0003-1852-4913)
- Shant Malkasian (ORCID: https://orcid.org/0000-0002-6478-4321)
- Gudrun Feuchtner (ORCID: https://orcid.org/0000-0001-6755-4399)
- Fabian Plank (ORCID: https://orcid.org/0000-0002-1861-9480)
- Ji Hyun Lee (ORCID: https://orcid.org/0000-0003-1831-6735)
- Yong‐Jin Kim (ORCID: https://orcid.org/0000-0002-1366-432X)
- Sang‐Eun Lee (ORCID: https://orcid.org/0000-0001-6645-4038)
- Subhi J. Al’Aref (ORCID: https://orcid.org/0009-0003-6667-2037)
- Matthew J. Budoff
- Wijnand J. Stuijfzand
- Alexander van Rosendael
Institutions
- Brigham and Women's Hospital (US)
- Baptist Hospital of Miami (US)
- Innsbruck Medical University (AT)
- University of Ottawa (CA)
- University of Urbino (IT)
- George Washington University (US)
- University of California, Irvine (US)
- University of Virginia Health System (US)
- Severance Hospital (KR)
- Leiden University Medical Center (NL)
- UCLA Medical Center (US)
- Seoul National University Hospital (KR)
- Accademia di Belle Arti di Urbino (IT)
- University of California San Diego (US)
- Centro Cardiologico Monzino (IT)
- Amsterdam Neuroscience (NL)
- Colegio Libre de Estudios Universitarios (MX)
- Northeast Georgia Medical Center (US)
- Hospital da Luz (PT)
- Beaumont Hospital, Royal Oak (US)
- University of California San Diego Medical Center (US)
- CVPath Institute (US)
- Gangnam Severance Hospital (KR)
- St. Paul's Hospital (CA)
- National Heart Centre Singapore (SG)
- Deutsches Herzzentrum München (DE)
- Catholic Kwandong University International St. Mary's Hospital (KR)
- Hanyang University Medical Center (KR)
- Fondazione Toscana Gabriele Monasterio (IT)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Harbor–UCLA Medical Center (US)
- University of Arkansas for Medical Sciences (US)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- The University of Texas Health Science Center at Houston (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Radiology Cardiothoracic Imaging
- Published
- 2026-07-23
- DOI
- https://doi.org/10.1148/ryct.250117
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health