Meaningful oversight of medical AI beyond human in the loop

Human oversight of medical AI is increasingly required, but clinician presence alone does not make oversight meaningful. We propose four interlocking conditions—epistemic capacity, cognitive space, decisional authority, and intervention effectiveness—that determine whether human judgment can function as a safety mechanism. Embedding these conditions across procurement, deployment, monitoring, and decommissioning can turn oversight into an operational patient-safety capability across predictive, generative, semi-autonomous, and agentic systems.

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Publication Details

Journal
npj Digital Medicine
Published
2026-07-23
DOI
https://doi.org/10.1038/s41746-026-02971-1
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Meaningful oversight of medical AI beyond human in the loop

Davy van de Sande, Nicoleta Economou‐Zavlanos, Michel E. van Genderen
npj Digital Medicine
Artificial Intelligence in Healthcare and Education
article

Meaningful oversight of medical AI beyond human in the loop

Davy van de Sande, Nicoleta Economou‐Zavlanos, Michel E. van Genderen
article en

Abstract

Human oversight of medical AI is increasingly required, but clinician presence alone does not make oversight meaningful. We propose four interlocking conditions—epistemic capacity, cognitive space, decisional authority, and intervention effectiveness—that determine whether human judgment can function as a safety mechanism. Embedding these conditions across procurement, deployment, monitoring, and decommissioning can turn oversight into an operational patient-safety capability across predictive, generative, semi-autonomous, and agentic systems.

npj Digital MedicineVol. 9(1)
Duke University (US), Erasmus MC (NL), Erasmus University Rotterdam (NL)
Peace, Justice and strong institutions
Openalex Percentile: Top 12%
Artificial Intelligence in Healthcare and Education
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