Considerations in Genomic Therapy Matching

To the Editor We read with great interest the cohort study by Lin et al1 on evidence grading for genomic therapy matching in rare and refractory cancers. The question is clinically important, but several issues may affect the interpretation of the main findings.

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Publication Details

Journal
JAMA Oncology
Published
2026-07-23
DOI
https://doi.org/10.1001/jamaoncol.2026.2251
Primary Topic
Genomic variations and chromosomal abnormalities
Type
article
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article

Considerations in Genomic Therapy Matching

Gang Tian, Ningran Zhang
JAMA Oncology
Genomic variations and chromosomal abnormalities
article

Considerations in Genomic Therapy Matching

Gang Tian, Ningran Zhang
article en

Abstract

To the Editor We read with great interest the cohort study by Lin et al1 on evidence grading for genomic therapy matching in rare and refractory cancers. The question is clinically important, but several issues may affect the interpretation of the main findings.

JAMA Oncology
Leshan Normal University (CN), Affiliated Hospital of Southwest Medical University (CN), Fourth Affiliated Hospital of China Medical University (CN)
Openalex Percentile: Top 9%
Genomic variations and chromosomal abnormalities
DOISourceOpenAlex
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Considerations in Genomic Therapy Matching — Gang Tian, Ningran Zhang · JAMA Oncology (2026) | TGRS Research Map | TGRS