Cox Dependent Deep Partially Linear Cox Model

Dependent censoring can bias conventional survival analyses, while nonlinear covariate effects challenge interpretable Cox modeling. We propose a copula-based deep partially linear Cox model (CD-DPLCM) that jointly models event and censoring times using a Frank copula. Linear effects remain directly interpretable, whereas deep neural networks capture multivariate nonlinear effects. Baseline hazards are approximated by B-splines, and all components, including the dependence parameter, are estimated through full likelihood. We also develop efficient-score-based inference for the finite-dimensional parameters. Simulations assess estimation accuracy and uncertainty quantification across different sample sizes, censoring rates, dependence strengths, and nonlinear structures, with comparisons against conventional Cox and copula-based proportional hazards methods. The framework offers flexible and interpretable survival analysis when the independent-censoring assumption is untenable.

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Publication Details

Journal
California Digital Library
Published
2026-07-23
DOI
https://doi.org/10.48321/d1860f8a4c
Primary Topic
Statistical Methods and Inference
Type
article
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article

Cox Dependent Deep Partially Linear Cox Model

RC Li
California Digital Library
Statistical Methods and Inference
article

Cox Dependent Deep Partially Linear Cox Model

RC Li
article en

Abstract

Dependent censoring can bias conventional survival analyses, while nonlinear covariate effects challenge interpretable Cox modeling. We propose a copula-based deep partially linear Cox model (CD-DPLCM) that jointly models event and censoring times using a Frank copula. Linear effects remain directly interpretable, whereas deep neural networks capture multivariate nonlinear effects. Baseline hazards are approximated by B-splines, and all components, including the dependence parameter, are estimated through full likelihood. We also develop efficient-score-based inference for the finite-dimensional parameters. Simulations assess estimation accuracy and uncertainty quantification across different sample sizes, censoring rates, dependence strengths, and nonlinear structures, with comparisons against conventional Cox and copula-based proportional hazards methods. The framework offers flexible and interpretable survival analysis when the independent-censoring assumption is untenable.

California Digital Library
Chinese University of Hong Kong (HK)
Peace, Justice and strong institutions
Openalex Percentile: Top 7%
Statistical Methods and Inference
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