Drug-Drug Interaction Between Praziquantel and Nevirapine in HIV-Schistosomiasis Co-infection: A Pharmacokinetic case report
Highlights Praziquantel (PZQ) is metabolized predominantly by CYP450 enzymes.Nevirapine (NVP) is a moderate inducer of CYP3A4 and CYP2B6.NVP and PZQ drug interactions have not been described.Our results indicate an absence of significant clinical or pharmacokinetic interaction between PZQ and NVP
Authors
- Lê Mg
- Hélène Marty
- Gilles Peytavin (ORCID: https://orcid.org/0000-0002-4359-537X)
- Firouzé Bani‐Sadr (ORCID: https://orcid.org/0000-0001-8268-866X)
- Arthur Lefevre
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Hôpital Bichat-Claude-Bernard (FR)
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- Journal of Travel Medicine
- Published
- 2026-07-23
- DOI
- https://doi.org/10.1093/jtm/taag066
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00