Directional purine pyrimidine asymmetry in CRISPR repeats facilitates spacer acquisition

MATLAB codes for analyzing purine–pyrimidine asymmetry in CRISPR direct repeats and modeling sequence-dependent DNA unzipping kinetics underlying spacer acquisition.

Authors

Hemachander Subramanian (ORCID: https://orcid.org/0000-0002-4869-5994)
Parthasarathi Sahu
S Barik
Ghosh Koushik

Institutions

National Institute of Technology Durgapur (IN)
Moffitt Cancer Center (US)

Publication Details

Journal: Zenodo (CERN European Organization for Nuclear Research)
Published: 2026-07-23
DOI: https://doi.org/10.5281/zenodo.21504154
Primary Topic: CRISPR and Genetic Engineering
Type: article
Field-Weighted Citation Impact: 0.00

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article

Directional purine pyrimidine asymmetry in CRISPR repeats facilitates spacer acquisition

Hemachander Subramanian, Parthasarathi Sahu, S Barik, Ghosh Koushik

Jul 23, 2026

Zenodo (CERN European Organization for Nuclear Research)

CRISPR and Genetic Engineering

article

Directional purine pyrimidine asymmetry in CRISPR repeats facilitates spacer acquisition

Hemachander Subramanian, Parthasarathi Sahu, S Barik, Ghosh Koushik

July 23, 2026article en

Abstract

MATLAB codes for analyzing purine–pyrimidine asymmetry in CRISPR direct repeats and modeling sequence-dependent DNA unzipping kinetics underlying spacer acquisition.

Zenodo (CERN European Organization for Nuclear Research)

National Institute of Technology Durgapur (IN), Moffitt Cancer Center (US)

Openalex Percentile: Top 15%

CRISPR and Genetic Engineering

DOI Open Access PDF OpenAlex

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Directional purine pyrimidine asymmetry in CRISPR repeats facilitates spacer acquisition — Hemachander Subramanian, Parthasarathi Sahu, et al. · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS